Funding-NIH - Single Cell Studies in Aging Research (R01)(R21); February 5, 2012

 

Please note that the funding announcement below is also available through an additional funding mechanism as an R21 (http://grants.nih.gov/grants/guide/pa-files/PA-11-321.html).  

Department of Health and Human Services

Participating Organization(s)

National Institutes of Health (NIH)

Components of Participating Organizations

National Institute on Aging (NIA)

Funding Opportunity Title

Single Cell Studies in Aging Research (R01)

Activity Code

R01 Research Project Grant  

Announcement Type

New

Related Notices

None

Funding Opportunity Announcement (FOA) Number

PA-11-320

Companion FOA

PA-11-321, R21 Exploratory/Developmental Grant

Number of Applications

See Section III. 3. Additional Information on Eligibility.

Catalog of Federal Domestic Assistance (CFDA) Number(s)

93.866, 93.838

FOA Purpose

This FOA issued by the National Institute on Aging (NIA), National Institutes of Health, encourages grant applications from institutions/organizations that propose to develop research on single cell biology to enhance the understanding of the mechanisms of normal aging and of age-related diseases.  Applications using -omics technologies, imaging, optofluidic platforms, mass spectroscopy, whole genome sequencing, and other tools and technologies at the single cell level are encouraged since it is expected that the single cell approach will improve the determination of unique and biologically significant properties of tissues and organs during the aging process.

Although we know that cells are heterogeneous, for example they might be at different stages in the cell cycle or at different stages in tumor progression, most contemporary studies use population of cells, thus providing a limited average view of cellular and tissue function.  This is due mainly to the lack of tools to study single cells.  This is now changing.  Advances in technology have made more single cell studies feasible and will convert cellular heterogeneity from a source of noise to a source of new discoveries.

Key Dates

Posted Date

August 24, 2011

Open Date (Earliest Submission Date)

September 5, 2011

Letter of Intent Due Date

Not Applicable

Application Due Date(s)

Standard dates apply, by 5:00 PM local time of applicant organization.

AIDS Application Due Date(s)

Standard dates apply, by 5:00 PM local time of applicant organization.

Scientific Merit Review

Standard dates apply

Advisory Council Review

Standard dates apply

Earliest Start Date(s)

Standard dates apply

Expiration Date

September 8, 2014

Due Dates for E.O. 12372

Not Applicable

Required Application Instructions

It is critical that applicants follow the instructions in the SF 424 (R&R) Application Guide except where instructed to do otherwise (in this FOA or in a Notice from the NIH Guide for Grants and Contracts). Conformance to all requirements (both in the Application Guide and the FOA) is required and strictly enforced. Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.

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Link to Full Announcement

 

http://grants.nih.gov/grants/guide/pa-files/PA-11-320.html