Funding-Consortium of Food Allergy Research (CoFAR) and CoFAR Statistical and Clinical Coordinating Center; October 9, 2009

Announcement Type
This Funding Opportunity Announcement (FOA) is a reissue of RFA-AI-04-034.

Request For Applications (RFA) Number: RFA-AI-09-039

Catalog of Federal Domestic Assistance Number(s)
93.855,  93.847

Key Dates
Release Date: July 7, 2009
Letters of Intent Receipt Date: October 9, 2009
Application Receipt Date: November 10, 2009
Peer Review Date: March, 2010
Council Review Date: May 2010
Earliest Anticipated Start Date: July 2010
Additional Information To Be Available Date (Url Activation Date): http://www.niaid.nih.gov/ncn/qa/revniaid.htm
Expiration Date: November 11, 2009

Due Dates for E.O. 12372

Not Applicable.

Additional Overview Content

Executive Summary

• Purpose.  This FOA issued by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), solicits grant applications for the continuation and expansion of the Consortium of Food Allergy Research (CoFAR). The Consortium will consist of a collaborative clinical research program to develop new approaches to treat and prevent IgE-mediated food allergy, including food allergy-associated anaphylaxis and food allergy-associated eosinophilic gastrointestinal disease (EGID). Within the context of these disorders, the goals of the program are to: (1) develop immune intervention strategies for prevention and treatment, (2) identify the mechanisms underlying the natural histories of these disorders, and (3) define the genetic components of these disorders. The consortium may consist of both collaborative multi-project as well as individual research projects. In addition this FOA will provide support for one Statistical and Clinical Coordinating Center (SACCC) to support the clinical research.
• Mechanism of Support. This FOA will utilize the U19 (multi-project) and U01 (single project) cooperative agreement award mechanisms.
• Funds Available and Anticipated Number of Awards. The total amount of funding that NIAID and NIDDK expect to award through this announcement in FY10 is $5.25 million in total costs, which includes $3.65 million in total costs for one to three CoFAR U19 and/or U01 research awards and $1.6 million in total costs for one CoFAR SACCC U01 award. 
• Budget and Project Period. NIAID and NIDDK expect to award through this announcement $3.65 million for one to three U19 and/or U01 CoFAR research program awards and $1.6 million for one U01 CoFAR SACCC award. An applicant may request a project period of up to 5 years.
• Eligible Institutions/Organizations. Institutions/organizations listed in Section III, 1.A. are eligible to apply.
• Eligible Project Directors/Principal Investigators (PDs/PIs). Individuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
• Number of PDs/PIs. More than one PD/PI (i.e., multiple PDs/PIs), may be designated on the application.
• Number of Applications.  Applicants may submit only a single application in response to this FOA, either a U19 or U01 CoFAR research grant application or a U01 CoFAR SACCC application. Individuals may only be a PD/PI, or Project Leader (PL) on one application.
• Resubmissions.  Resubmission applications are not permitted in response to this FOA
• Renewals. Renewal applications are permitted in response to this FOA.
• Special Date(s). This FOA uses non-standard due dates. See Receipt, Review and Anticipated Start Dates.

Application Materials. See Section IV.1 for application materials