Funding-Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01); November 24, 2009

Announcement Type
This Funding Opportunity Announcement (FOA) is a reissue of RFA-GM-09-008.   

Request for Applications (RFA) Number: RFA-GM-10-009

NOTICE: Applications submitted in response to this Funding Opportunity Announcement (FOA) for Federal assistance must be submitted electronically through Grants.gov (http://www.grants.gov) using the SF424 Research and Related (R&R) forms and the SF424 (R&R) Application Guide.

APPLICATIONS MAY NOT BE SUBMITTED IN PAPER FORMAT.

This FOA must be read in conjunction with the application guidelines included with this announcement in Grants.gov/Apply for Grants (hereafter called Grants.gov/Apply).

A registration process is necessary before submission and applicants are highly encouraged to start the process at least four (4) weeks prior to the grant submission date. See Section IV.

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Catalog of Federal Domestic Assistance Number(s)
93.859, 93.394, 93.395, 93.396, 93.399, 93,866, 93.273, 93,279, 93.121, 93.242, 93.853, 93.879

Key Dates  
Release/Posted Date:  September 17, 2009
Opening Date:  October 24, 2009 (Earliest date an application may be submitted to Grants.gov)
Letters of Intent Receipt Date(s): not required
NOTE: On-time submission requires that applications be successfully submitted to Grants.gov no later than 5:00 p.m. local time (of the applicant institution/organization). 
Application Due Date(s):  November 24, 2009
Peer Review Date(s): March/April 2010
Council Review Date(s): May 2010
Earliest Anticipated Start Date(s): July 1, 2010
Additional Information To Be Available Date (Activation Date): Not Applicable. Frequently Asked Questions (FAQs) at http://www.nigms.nih.gov/Research/Application/EurekaFAQs.htm
Expiration Date: November 25, 2009

Due Dates for E.O. 12372

Not Applicable

Additional Overview Content

Executive Summary

• Purpose. This FOA solicits Research Project Grant (R01) applications from institutions/organizations proposing exceptionally innovative research on novel hypotheses or difficult problems, solutions to which would have an extremely high impact on biomedical or biobehavioral research that is germane to the mission of one or more of the participating NIH Institutes. This FOA is for support of new projects, not continuation of projects that have already been initiated. It does not support pilot projects, i.e., projects of limited scope that are designed primarily to generate data that will enable the PI to seek other funding.
• Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism.
• Funds Available and Anticipated Number of Awards. NIGMS ($6 million, 18-22 awards), NCI ($3 million, 9-11 awards), NIA ($1 million, 2-3 awards), NIAAA ($600,000, 2 awards), NIDCR ($800,000, 2-3 awards), NIDA ($1 million, 3-4 awards), NIMH ($3 million, 8-12 awards), NINDS ($2 million, 6 awards), and NLM ($985,000, 3 awards) are participating in this initiative. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. 
• Budget and Project Period. Support may be requested for up to $800,000 in direct costs (excluding consortium Facilities and Administrative [F&A] costs) over a four-year period, prorated for shorter terms ($600,000 for three years, $400,000 for two years). Regardless of the term of support, direct costs (excluding consortium F&A costs) may not exceed $250,000 in any one year.
• Application Research Plan Component Length: The R01 application Research Plan component of the PHS398 may not exceed 7 pages, including tables, graphs, figures, diagrams, and charts.
• Eligible Institutions/Organizations. Institutions/organizations listed in Section III, 1.A. are eligible to apply.
• Eligible Project Directors/Principal Investigators (PDs/PIs). Individuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/ organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
• Number of PDs/PIs. More than one PD/PI (i.e., multiple PDs/PIs) may be designated on the application.
• Number of Applications. Applicants may submit more than one application, provided each application is scientifically distinct.
• Resubmissions.    Resubmission applications are not permitted in response to this FOA.
• Renewals. Renewal applications are not permitted in response to this FOA.
• Special Date(s). This FOA uses non-standard due dates. See Receipt, Review and Anticipated Start Dates.
• Application Materials. See Section IV.1 for application materials.
• General Information. For general information on SF424 (R&R) Application and Electronic Submission, see these Web sites:
• SF424 (R&R) Application and Electronic Submission Information: http://grants.nih.gov/grants/funding/424/index.htm
• General information on Electronic Submission of Grant Applications: http://era.nih.gov/ElectronicReceipt/
• Hearing Impaired. Telecommunications for the hearing impaired are available at: TTY:  (301) 451-5936

For Further Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-GM-10-009.html