Funding-Mechanistic Research on
Complementary and Alternative
Medicine Products (R01);November 1,
2010
Key
Dates
Release/Posted Date:
August 23, 2010
Opening Date: November 1, 2010
(Earliest date an application may be submitted to Grants.gov)
Letters of
Intent Receipt Date(s): November 1, 2010, February 1, 2011,
September 30, 2011, February 1, 2012, September 30,
2012.
NOTE: On-time submission requires that applications be successfully
submitted to Grants.gov no later than 5:00 p.m. local time (of the applicant
institution/organization).
Application Due
Date(s): December 1, 2010, March 1, 2011,
November 1, 2011, March 1, 2012, November 1, 2012
AIDS
Application Due Date(s): Not Applicable
Peer Review
Date(s): March 2011, June 2011, March 2012,
June 2012, March 2013
Council Review Date(s):
May
2011, October 2011, May 2012, October 2012, May 2013
Earliest Anticipated Start
Date(s): July 2011, December 2011, July 2012,
December 2012, July 2013
Additional
Information To Be Available Date (Activation Date): Not
Applicable
Expiration Date: November 2, 2012
Due Dates for E.O.
12372
Not
Applicable
Additional Overview
Content
Executive
Summary
- Purpose.
This FOA issued by
the National Center for Complementary and Alternative Medicine (NCCAM) in
collaboration with the Office of Dietary Supplements (ODS), at the National
Institutes of Health, invites Research Project Grant (R01) applications to
study the potential mechanisms of action of promising CAM natural products
(NPs). Natural products are widely used by Americans for health purposes.
Knowledge about the active components, their molecular and cellular targets,
as well as markers of potential beneficial or harmful biological effects
are critical pieces of preliminary information needed to insure maximally
informative clinical efficacy studies on these products. Research on the
development of improved methodology for the isolation and characterization of
constituents of natural products and on their determination in the natural
matrix will also be supported under this initiative.
- Mechanism of
Support. This FOA will
utilize the R01 award
mechanism.
- Funds Available and
Anticipated Number of Awards. NIH participants
are contributing $8.1 million in total to this FOA. The total amount to be
awarded in the first year is approximately $1.625 million (total costs).
Approximately 2-4 awards are anticipated. The total amount to be awarded in
the second and third year is approximately $3.25 million (total costs).
Approximately 5-7 awards are anticipated per year. Awards issued under this
FOA are contingent upon the availability of funds and the submission of a
sufficient number of meritorious applications.
- Budget and Project
Period. Budgets for direct
costs of up to $300,000 per year and a project duration of up to five years
may be requested for a maximum of $1,500,000 direct costs over a five-year
project period.
- Application
Research Strategy Length: The R01 Research
Strategy section may not exceed 12 pages, including tables, graphs, figures,
diagrams, and charts. See http://grants1.nih.gov/grants/funding/funding_program.htm,
- Eligible
Institutions/Organizations. Institutions/organizations listed in
Section
III, 1.A. are eligible to
apply.
- Eligible Project
Directors/Principal Investigators (PDs/PIs). Individuals
with the skills, knowledge, and resources necessary to carry out the proposed
research are invited to work with their institution/ organization to develop
an application for support. Individuals from underrepresented racial and
ethnic groups as well as individuals with disabilities are always encouraged
to apply for NIH support.
- Number of
PDs/PIs. More than one
PD/PI (i.e., multiple PDs/PIs) may be designated on the application.
- Number of
Applications. Applicants may
submit more than one application, provided each application is scientifically
distinct.
- Resubmissions.
Applicants may
submit a resubmission application previously submitted to this FOA,Such applications must
include an Introduction addressing the previous peer review critique (Summary
Statement). See new NIH policy on resubmission (amended) applications
(NOT-OD-09-003,
NOT-OD-09-016).
- Renewals.
Renewal
applications are not permitted in response to this FOA.
- Special
Date(s). This FOA uses
non-standard due dates. See Receipt,
Review and Anticipated Start Dates.
- Application
Materials. See Section
IV.1 for application
materials.
- General
Information. For general
information on SF424 (R&R) Application and Electronic Submission, see
these Web sites:
- Hearing
Impaired. Telecommunications for the hearing
impaired are available at: TTY: (301)
451-5936
For Further
Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-AT-11-001.html