(FOA)-Understanding 
the Rules of Life: Microbiome Theory and Mechanisms (URoL:MTM); January 17, 
2020
Agency
National
 Science Foundation
Description
The 
URoL:MTM program invites
 integrated, interdisciplinary proposals that develop theoretical predictive
 frameworks with well-designed experimental and/or computational approaches to
 generate and test hypotheses about the causal relationships within the
 microbiome, and among the microbiome, host, and environment. How these
 relationships affect robustness, resilience, and adaptability of individual
 organisms, populations, and communities are also of interest. Projects may
 apply existing ecological and evolutionary theory or develop new experimental,
 computational, or mathematical tools, models, and theory to: i) 
explain function and interactions in natural, experimental, and model 
microbiomes; ii) elucidate the molecular mechanisms that underlie communication 
between the host and the microbiome and among the members of the microbiome; 
and/or iii) comparatively analyze microbiomes to discover emergent properties 
that provide insight into the behavior of living systems.
Successful
 projects will contribute to a portfolio of research that identifies general
 principles ("rules") that underlie a wide spectrum of biological phenomena 
across spatial, temporal (from sub-second to geologic), and/or complexity 
(molecular, cellular, organismal, population) scales. URoL:MTM projects must 
integrate perspectives and research approaches from more than one research 
discipline (e.g., biology, chemistry, computer science, engineering, 
geosciences, mathematics, physics, social and behavioral sciences). They must 
also incorporate best practices regarding protocol documentation, sample 
selection, data collection and analysis, model/algorithm development, as well as 
data sharing and accessibility. The interdisciplinary scope of URoL:MTM projects should provide unique training and
 outreach opportunities to train the next generation of scientists in a
 diversity of scientific approaches and to engage society more 
generally.
Announcement
 Number:
NSF
 20-513
 
Closing
 Date:
Letter
 of Intent Due: January 17, 2020
Full
 Proposal Deadline: March 02, 2020
 
Link
 to Full Announcement
https://www.nsf.gov/pubs/2020/nsf20513/nsf20513.htm?WT.mc_id=USNSF_25&WT.mc_ev=click
Contact
 Information
Catalina 
Achim
(703)
 292-2048