(FOA)-Exploring the Mechanisms Underlying Analgesic Properties of Minor Cannabinoids and Terpenes (R01 Clinical Trial Optional); March 15, 2019

 

Agency:

National Center for Complementary and Integrative Health (NCCIH)

Description:

Through this funding opportunity announcement (FOA), the National Center for Complementary and Integrative Health (NCCIH) solicits research grant applications to study minor cannabinoids and terpenes in the cannabis plant as it relates to pain and nociception. Minor cannabinoids are defined as any and all cannabinoids from the cannabis plant other than Δ9-tetrahydrocannabinol (Δ9-THC). Cannabinoids and terpenes of particular interest include the following: Cannabidiol (CBD), Cannabigerol (CBG), Cannabinol (CBN), Cannabichromene (CBC), Myrcene, β-caryophyllene, Limonene, α-terpineol, Linalool, α-phellandrene, α-pinene, β-pinene, γ-terpinene, and α-humulene. This initiative intends to support highly innovative basic and/or mechanistic studies in appropriate model organisms and/or human subjects aiming to identify, describe and determine whether minor cannabinoids and/or terpenes can help treat pain. The mechanisms and processes underlying potential contribution of minor cannabinoids and terpenes to pain relief and functional restoration in patients with different pain conditions may be very broad. This initiative encourages interdisciplinary collaborations by experts from multiple fields—pharmacologists, chemists, physicists, physiologists, neuroscientists, psychologists, endocrinologists, immunologists, geneticists, behavioral scientists, clinicians, and others in relevant fields of inquiry.

Activity Code:

R01 Research Project Grant

 

Announcement Number:

RFA-AT-19-008

 

Closing Date:

March 15, 2019

 

Link to Full Announcement:

http://grants.nih.gov/grants/guide/rfa-files/RFA-AT-19-008.html

 

Companion Funding Opportunity:

R21 - http://grants.nih.gov/grants/guide/rfa-files/RFA-AT-19-009.html