FUNDING-Families
of SMA - Basic Research; September 8, 2017
Agency
Families
of SMA
curesma
Description
Families
of SMA has issued a Request for Proposals for research projects designed to
advance current understanding of spinal muscular atrophy disease. Grants of up
to $150,000 will be awarded for novel research focused on SMA disease pathology
at the molecular, cellular, and biochemical level; generating key reagents and
tools to facilitate drug development and clinical trials; and identifying new
therapeutic strategies for SMA.
To
be considered, studies should focus on the molecular and biochemical mechanisms
regulating SMN expression or mediating SMN function; developing greater
understanding of the pathophysiology of SMA using well-validated animal or
cellular models of the SMA; early proof-of-concept assessments of novel
therapeutic approaches for SMA in well-validated animal or cellular models of
the disease or on progressing aspects of ongoing preclinical drug programs for
SMA toward IND; and work that generates research or clinical trial tools for
SMA, such as new animal models, phenotypic cellular assays, activity assays for
SMN function, biomarkers or outcome measures for clinical trials, and newborn
screening protocols/technologies.
Closing
Date:
September
8, 2017
Link
to Full Announcement
Contact
Information
Jackie
Glascock, PhD